CryoCapsule

Bringing Correlative light and electron microscopy forward with the CryoCapsule

High pressure freezing is the most advanced technology when it comes to vitrify a hydrated biological specimen while preserving the ultrastructure. Developed in the 80's [1], the technology evolved progressively to become accessible to a larger community. Still, the sample preparation prior to HPF remains tedious and often comes to advance expertise depending on the specimen [2].

The CryoCapsule® is a new tool in the field of High Pressure Freezing (HPF) and correlative light and electron microscopy (CLEM). Comparable to a small petri dish, it is composed of a landmarked sapphire disc and a gold spacer ring (50 µm thick) maintained together by a plastic ring [3].

Cat #	Description	Pack
3750	Cryocapsule® 3mm	9 Pack
3751	Hpm010 Abra Fluid Adaptor	Each
3752	Hpm100 Leica Adaptor	10 Pack
3753	Décapsuleur	5 Pack
3754	Décapsuleur Pencil	Each
3755	Perforated Petri Dish For Live Cell Imaging	5 Pack